Beilstein J. Org. Chem.2020,16, 1875–1880, doi:10.3762/bjoc.16.155
catalyst effectively catalyzed Biginelli-like reactions with moderate to good enantioselectivities. Control experiments indicated that the presence of the two hydroxy groups were indispensable for achieving a high enantioselectivity.
Keywords: asymmetricBiginelli-likereaction; chiral 1,1,4,4